Prognostic Significance of ypN Status After Neoadjuvant Chemoimmunotherapy in NSCLC

A systematic review and meta-analysis evaluating the association between pathological nodal status after treatment and survival outcomes in resectable non-small cell lung cancer. The analysis includes two studies for overall survival and disease-free survival, with hazard ratios pooled from literature searches up to February 2026. The work was authored by Huan Shao and is available as a document.

Use Cases

• Evaluating the prognostic value of ypN status based on the pooled hazard ratios
• Assessing survival outcomes stratified by pathological nodal response
• Supporting clinical decision-making for neoadjuvant chemoimmunotherapy
• Designing future prospective studies with standardized endpoints

Strengths

• Pooled hazard ratios for OS (4.75) and DFS (3.54) with confidence intervals are provided
• Analysis follows PRISMA 2020 guidelines and includes a systematic review registration
• The document is licensed under CC-BY-4.0 for open sharing

Limitations

• The meta-analysis for OS and DFS each includes only two retrospective studies
• Row count and column-level documentation are unknown
• The description metadata is limited; actual data quality requires manual inspection after download

Provenance

Source

figshare

Collection Method

Systematic review and meta-analysis of literature from PubMed, Web of Science, Scopus, Embase, and Cochrane Library.

Time Range

Literature searched from inception to February 26, 2026.

Freshness

Last updated 2026-05-22 04:37:59