TyG Index and Renal Function Progression in 53,607 CKD Patients from China, 2005-2022

A Chinese multicenter retrospective cohort study of 53,607 patients with chronic kidney disease (CKD) stages 3–4 from the China Renal Data System (CRDS) between 2005 and 2022. The dataset likely contains longitudinal data on the association between the baseline triglyceride-glucose (TyG) index and renal function progression risk. It was authored by Fan Zhu and last updated on 2026-04-28.

Use Cases

• Predicting renal function progression risk based on the TyG index and other patient variables.
• Investigating the non-linear, U-shaped relationship between the TyG index and CKD progression mentioned in the results.
• Conducting subgroup analyses to assess the consistency of the TyG index association across different patient populations.
• Building competing-risk models for renal outcomes using all-cause death as a competing event.

Strengths

• Includes 53,607 patient records from a multicenter cohort.
• Features a median follow-up period of 31.18 months with 19,619 progression events.
• Analysis includes multivariate Cox models, restricted cubic splines, and sensitivity tests, suggesting a structured analytical dataset.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is very small (15.1 KB), indicating it may contain only summary or analysis results rather than the raw patient-level data.

Provenance

Source

China Renal Data System (CRDS)

Collection Method

Multicenter retrospective cohort study

Time Range

2005 to 2022

Freshness

Last updated 2026-04-28 05:24:24; freshness should be verified.

Geography

China