Gastroschisis Prevalence in Canada by Conception Month and Latitude, 2006-2020

Shiliang Liu's population-based cohort study analyzes the prevalence of gastroschisis among infants conceived in Canada between April 2006 and March 2020. The dataset likely contains tabular data on gastroschisis rates, conception months, geographic latitudes, and rural/urban residence. Findings indicate a protective effect of periconceptional sunlight exposure, with winter conception and northern latitudes associated with higher risk.

Use Cases

• Analyze seasonal patterns of gastroschisis risk based on conception month.
• Model geographic risk gradients based on latitude indicators.
• Investigate interaction effects between seasonality and rural/urban residence.
• Study hypothesized links between sunlight exposure, vitamin D, and birth defect etiology.

Strengths

• Population-based cohort covering conceptions from April 2006 to March 2020.
• Provides specific prevalence rates (e.g., 4.6 per 10,000 for winter conceptions).
• Includes adjusted rate ratios (aRR) with confidence intervals for key associations.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Data is stored in a DOCX file (25.4 KB), suggesting a small, potentially summary-level dataset.

Provenance

Source

Shiliang Liu

Collection Method

Population-based cohort study using log-binomial regression with a Poisson distribution.

Time Range

April 2006 to March 2020

Freshness

Last updated 2026-05-05 04:10:07; freshness should be verified.

Geography

Canada