Serum Metabolomic Profiles for Early Detection of Avian Reovirus in Broiler Chickens
by Asha Ranaraja·Updated 29d ago
71.9 KB1files
Available on 1 platform
Sign in to view source links and access this dataset
Description
150 serum samples from avian reovirus (ARV)-challenged and control broiler chickens, collected at 24, 48, and 72 hours post-infection. The dataset, created by Asha Ranaraja and last updated in May 2026, contains 587 detected metabolites analyzed via LC-MS/MS to identify early biomarkers like LysoPC and PC depletion.
Use Cases
Identify early diagnostic biomarkers for avian reovirus infection based on lipid metabolite levels.
Train machine learning models for disease classification using the 587 detected serum metabolites.
Analyze metabolic pathway alterations in response to viral infection, such as arginine-proline metabolism.
Validate non-invasive screening methods for poultry flock health surveillance.
Strengths
Includes 150 serum samples with temporal resolution at three post-infection time points.
Profiles 587 metabolites, with differential expression analysis identifying 371, 96, and 402 metabolites at 24, 48, and 72 hours respectively.
Specific biomarkers like LysoPC a C14:0 are reported with high diagnostic performance (AUC ≈ 1.00).
Limitations
Row count is unknown, which may limit suitability assessment.
Column-level documentation is absent; field semantics must be inferred after download.
The dataset is small (71.9 KB), indicating limited scope.
Provenance
Source
figshare
Collection Method
Serum samples analyzed via liquid chromatography–tandem mass spectrometry (LC–MS/MS) with preprocessing including standardization, log2 transformation, and batch correction.
Time Range
Samples collected at 24, 48, and 72 hours post-infection.
Freshness
Last updated 2026-05 08 05:51:21; freshness should be verified.