Hospitalized AECOPD Patient Trial Data on Severity-Adapted Exercise Rehabilitation

141 hospitalized patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) were enrolled in a randomized controlled trial. The dataset likely contains results comparing severity-adapted graded exercise rehabilitation to conventional rehabilitation on systemic inflammatory biomarkers and functional capacity measures. The data was uploaded by Hui Zeng to figshare under a CC-BY-4.0 license.

Use Cases

• Compare the effects of different exercise intensities on inflammatory markers like IL-6, IL-8, and TNF-α.
• Analyze the relationship between disease severity (Grade I-III) and improvements in functional capacity measured by the 6-minute walk test.
• Model patient outcomes based on treatment group and symptom scores from the COPD Assessment Test (CAT) and Hospital Anxiety and Depression Scale (HADS).
• Investigate the anti-inflammatory response patterns between intervention and control groups using biomarker data.

Strengths

• Data originates from a prospective, assessor-blinded randomized controlled trial with 141 participants.
• Includes multiple primary outcome measures: five systemic inflammatory biomarkers (IL-6, IL-8, TNF-α, hs-CRP, WBC).
• Includes multiple secondary outcome measures: functional and symptom scores (6MWT, mMRC, CAT, HADS).
• Patients were stratified by disease severity (Grade I-III), allowing for severity-specific analysis.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is small (698.8 KB), indicating limited scope.

Provenance

Source

figshare

Collection Method

Data collected from a clinical trial (ChiCTR2300072409).

Time Range

Temporal coverage of the trial is not specified in the provided metadata.

Freshness

Last updated 2026-04-16 04:20:26; freshness should be verified.

Geography

Spatial coverage is not specified in the provided metadata.