Single-Cell and Spatial Transcriptomic Profiling of PTPRR in Pancreatic Cancer

Runyang Li's dataset, last updated May 13, 2026, contains results from an integrated analysis of pancreatic ductal adenocarcinoma (PDAC). It includes data from public datasets like TCGA-PAAD and GSE79668, focusing on the expression and role of the PTPRR gene in PDAC metastasis.

Use Cases

• Identify prognostic biomarkers for pancreatic cancer based on PTPRR expression levels.
• Investigate tumor-stroma interactions in pancreatic cancer based on single-cell and spatial transcriptomic analyses.
• Study the link between gene expression and immune microenvironment in metastatic cancer based on TGFβ, CCL, and CXCL pathway data.
• Validate the association between KRAS/TP53 mutations and gene expression signatures in pancreatic cancer.

Strengths

• Integrates data from multiple public sources, including TCGA-PAAD and GSE79668.
• Includes results from in vitro functional assays (MTT, Transwell) and plasmid transfection.
• License is CC-BY-4.0, allowing for open sharing and reuse.

Limitations

• Dataset is very small (1.1 KB), suggesting it contains summary results rather than raw expression data.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.

Provenance

Source

figshare

Collection Method

Integrated analysis of public datasets and original in vitro experiments.

Freshness

Last updated 2026-05-13 05:57:41; freshness should be verified.