Glioblastoma Tumor-Associated Macrophage Heterogeneity Review

Figshare hosts a 10.8 KB XLSX file by Jun Lu, containing a literature review on the spatiotemporal and metabolic heterogeneity of tumor-associated macrophages in glioblastoma. The review synthesizes single-cell and spatial multi-omics data to propose a therapeutic framework. The dataset's row and column counts are unknown.

Use Cases

• Extract therapeutic targets like the CD47-SIRPα axis for phagocytosis checkpoint blockade analysis.
• Analyze spatial enrichment patterns of TAM subsets such as BAMs in perivascular zones.
• Study metabolic interactions like lactate-driven histone lactylation for metabolic-epigenetic interference strategies.
• Map lineage competition dynamics between microglia, BAMs, and BMDMs during tumor evolution.

Strengths

• File is openly licensed under CC BY 4.0.
• Content is based on the latest single-cell and spatial multi-omics data.
• Review provides an integrative framework covering spatiotemporal, metabolic, and therapeutic dimensions.

Limitations

• Dataset is a 10.8 KB review document, not a primary data table with rows and columns for computational analysis.
• No sample data or defined columns are provided, limiting direct use for quantitative modeling.
• The file's small size indicates it contains summary text and concepts, not extensive raw datasets.

Provenance

Source

Jun Lu via figshare.

Collection Method

Literature review synthesizing published single-cell and spatial multi-omics studies.

Time Range

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Freshness

Last updated March 26, 2026.

Geography

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