Spindle-to-Oocyte Light Retardance Ratio for Oocyte Quality Assessment

581 mature oocytes from women aged ≤ 38 years undergoing IVF cycles at Lee Women’s Hospital were studied from August 2024 to August 2025. Chun-I Lee authored this prospective cohort study using polarized light microscopy to measure birefringence signals. The dataset likely contains measurements of spindle and zona pellucida birefringence, developmental outcomes, and time-lapse analysis results.

Use Cases

• Predict usable blastocyst formation based on spindle-to-oocyte light retardance ratio (SOLRR)
• Compare embryonic progression speed based on SOLRR groups using time-lapse analysis data
• Assess trophectoderm morphology correlation with birefringence signals
• Identify oocytes with superior developmental competence based on visible metaphase II spindle

Strengths

• 581 mature oocytes provide a substantial sample size for analysis
• Prospective cohort study design from August 2024 to August 2025 offers recent clinical data
• Multivariate analysis identified SOLRR and anti-Müllerian hormone as significant predictors

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• Data is limited to a single hospital (Lee Women’s Hospital) and women aged ≤ 38 years

Provenance

Source

Lee Women’s Hospital

Collection Method

Polarized light microscopy measurements on oocytes prior to intracytoplasmic sperm injection, with subsequent embryo culture in a time-lapse system.

Time Range

August 2024 to August 2025

Freshness

Last updated 2026-05-05 04:13:03; freshness should be verified