Lymph Node Yield Thresholds for Oral Cancer Surgery After Neoadjuvant Therapy

A clinical study dataset defines and validates lymph node yield thresholds predictive of survival for oral squamous cell carcinoma patients undergoing neck dissection after neoadjuvant immunochemotherapy. It comprises data from 256 patients in a training cohort and 199 in an external validation cohort, collected from hospitals in China between 2019 and 2022. The research was authored by Shuai Yuan and published on figshare.

Use Cases

• Establishing surgical quality benchmarks based on defined lymph node yield thresholds.
• Validating prognostic models for overall and disease-free survival in oral cancer patients.
• Analyzing the association between lymph node yield and post-operative complication rates.
• Comparing survival outcomes between patients meeting 'Adequate' versus 'Inadequate' surgical thresholds.

Strengths

• Defines specific, validated thresholds (20 nodes for unilateral, 18 per side for bilateral dissection) with associated hazard ratios.
• Includes an external validation cohort of 199 patients, supporting the robustness of findings.
• Reports model performance metrics, including a C-index of 0.71 for overall survival.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Data may reflect geographic and temporal bias inherent to the two Chinese hospital sources.

Provenance

Source

Henan Cancer Hospital and the First Affiliated Hospital of Zhengzhou University.

Collection Method

Retrospective analysis of patient records from consecutive and independent cohorts.

Time Range

2019-2022

Freshness

Last updated 2026-06-03 05:43:02; freshness should be verified.

Geography

China