Mouse Weight and Metabolite Data for 2,3-Butanediol Isomer Study

A 2026 study by Sunil Veeravalli investigating the effects of 2,3-butanediol isomers on mice fed a fat-enriched diet. The dataset includes measurements of weight, plasma and liver metabolite concentrations, and gut microbiota composition. It was published on figshare under a CC-BY-4.0 license.

Use Cases

• Analyzing the anti-obesogenic effects of specific 2,3-butanediol isomers based on weight gain and plasma glucose data.
• Investigating liver metabolite changes in response to dietary interventions based on the 693 identified liver metabolites.
• Studying the relationship between gut microbiota composition (e.g., Bacteroidota, Actinomycetota phyla) and metabolic health outcomes.
• Evaluating potential therapeutic agents for weight control based on the experimental results with 2R,3R-butanediol.

Strengths

• Includes data on 693 identified liver metabolites, providing a detailed metabolic profile.
• Explicitly compares multiple treatment groups: untreated, three individual isomer treatments, and an isomer mix.
• Results are linked to specific biological mechanisms involving indolepropionate and Bifidobacterium species.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is small (37.4 KB), indicating limited scope and likely a small sample size.

Provenance

Source

Sunil Veeravalli

Collection Method

Experimental study with mice fed standard chow or a 16% fat-enriched diet, with subsequent treatment and analysis.

Freshness

Last updated 2026-05-25 09:59:35