Meta-Analysis of Sodium-Restricted Diet Effects on Heart Failure Patient Outcomes

16 randomized controlled trials involving 2,260 patients were analyzed to evaluate sodium restriction in heart failure. The meta-analysis found a sodium-restricted diet was associated with a 50% increased risk of all-cause mortality and a 151% increased risk of cardiac mortality. Author Ming-hao Ma published this systematic review and meta-analysis on figshare in May 2026.

Use Cases

• Assessing mortality risk associated with sodium restriction based on pooled results from 16 RCTs
• Investigating subgroup effects for HFrEF patients based on the described subgroup analysis
• Evaluating quality of life outcomes in heart failure dietary studies based on the descriptive analysis mentioned

Strengths

• Analysis includes 16 randomized controlled trials, a substantial number for a meta-analysis
• Pooled data covers 2,260 patients, providing a meaningful sample size
• Results include specific risk ratios with confidence intervals (e.g., RR 1.50 for all-cause mortality)

Limitations

• The dataset is a single 18.5 KB document, limiting the scope of raw data available
• Column-level documentation is absent; field semantics must be inferred from the manuscript
• Row count for the underlying trial data is unknown, which may limit suitability assessment

Provenance

Source

figshare

Collection Method

Systematic review and meta-analysis of RCTs retrieved from PubMed, Web of Science, Cochrane Library, and Embase.

Time Range

Retrieval period from database establishment to July 2025.

Freshness

Last updated 2026-05-01 05:28:27