Ketogenic vs Calorie-Restricted Diet Effects on Liver Disease: 102 Patient Study

102 MASLD patients completed a 12-week nutritional intervention comparing ketogenic and calorie-restricted diets. Wei-jie Sun authored this retrospective cohort study, which measured changes in liver fat, body composition, and metabolic biomarkers. The dataset likely contains patient-level results from FibroTouch scans, anthropometric measurements, and laboratory tests.

Use Cases

• Compare the efficacy of two diets on liver fat reduction based on Controlled Attenuation Parameter (CAP) scores.
• Analyze the relationship between diet type and changes in muscle mass based on body composition measurements.
• Model the impact of dietary intervention on fasting insulin levels based on laboratory biomarker data.
• Investigate correlations between reductions in visceral fat grade and improvements in liver steatosis severity.

Strengths

• Includes results from 102 patients, providing a moderate sample size for analysis.
• Contains specific, quantified outcomes such as median ΔCAP reductions of 62.0 dB/m for KD and 36.0 dB/m for CRD.
• Reports Cohen's d effect sizes for key comparisons, allowing for assessment of intervention magnitude.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is a 12.4 KB DOCX file, suggesting limited scope and likely summary tables rather than raw patient data.

Provenance

Source

figshare, author Wei-jie Sun.

Collection Method

Retrospective cohort study analyzing patients completing 12-week nutritional management.

Freshness

Last updated 2026-05-05 04:13:59; freshness should be verified.