A figshare dataset by Yayu Wang, last updated May 2026, presents results from an integrated analysis of miRNA-mRNA regulatory networks in Duchenne muscular dystrophy (DMD). The 13.8 KB Excel file likely contains tabular data supporting the identification of the miR-30c-5p/SOCS3 axis as a potential driver of inflammation and metabolic imbalance in DMD.
Use Cases
- Validate miRNA-mRNA regulatory networks based on integrated RNA-seq data mentioned in the description
- Investigate inflammatory pathway enrichment based on SOCS3 expression data
- Analyze metabolic process suppression in DMD muscle cells based on single-cell RNA-seq findings
Strengths
- Data is derived from integrated analysis of multiple RNA-seq datasets (GSE38417, GSE109178, GSE157668, GSE213925)
- Results were validated in mdx mice, C2C12 myoblasts, and primary skeletal muscle cells
- File is licensed under CC-BY-4.0 for open reuse
Limitations
- Row count is unknown, which may limit suitability assessment
- Column-level documentation is absent; field semantics must be inferred after download
- The dataset is very small (13.8 KB), indicating limited scope
Provenance
- Source
- figshare
- Collection Method
- Integrated bulk RNA-seq, small RNA-seq, and single-cell RNA-seq data analysis combined with differential expression, target prediction, and functional enrichment mapping.
- Freshness
- Last updated 2026-05-22 05:35:36; freshness should be verified