NFIA::CBFA2T3 Fusion in Pediatric Erythroid Sarcoma: A Molecular Case Report

A clinical case report describes a rare pediatric erythroid sarcoma with extensive extramedullary involvement. The report identifies an NFIA::CBFA2T3 chimeric fusion, proposing it as a marker for a molecularly defined leukemia subgroup. The dataset is a 32.5 KB document authored by Marta Brunetti, shared under a CC-BY-4.0 license and last updated in May 2026.

Use Cases

• Identifying potential molecular markers for rare leukemia subtypes based on the described NFIA::CBFA2T3 fusion.
• Studying the clinical presentation and treatment response of extramedullary erythroid sarcoma based on the detailed case description.
• Comparing genetic findings in erythroid malignancies to other myeloid neoplasms as suggested by the description's diagnostic context.

Strengths

• The report provides a detailed clinical description of a rare pediatric cancer case.
• It identifies a specific molecular fusion (NFIA::CBFA2T3) with potential diagnostic significance.
• The data is shared under a permissive CC-BY-4.0 license.

Limitations

• The dataset is a single case report (32.5 KB), offering limited statistical power for analysis.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.

Provenance

Source

Marta Brunetti via figshare.

Collection Method

Clinical case study and genomic analysis.

Freshness

Last updated 2026-05-04 10:39:10; freshness should be verified.