Prognostic Immune and Nutritional Index for Esophageal Cancer Survival

193 patients with esophageal squamous cell carcinoma were enrolled in a retrospective study to evaluate a prognostic index. The research, authored by Xiao Wu, establishes a PINI cutoff of 3.320 as an independent predictor for disease-free survival. Results show a significant difference in 3-year survival rates between patient cohorts with low and high PINI scores.

Use Cases

• Predicting disease-free survival in esophageal cancer patients based on the Prognostic Immune and Nutritional Index (PINI).
• Assessing overall survival risk stratification for patients receiving neoadjuvant immunochemotherapy.
• Validating the PINI cutoff value of 3.320 in independent cohorts of esophageal squamous cell carcinoma patients.
• Building personalized therapeutic strategy models by incorporating PINI into existing prognostic frameworks.

Strengths

• Includes data from 193 patients with esophageal squamous cell carcinoma.
• Provides specific hazard ratios and 95% confidence intervals for survival outcomes (e.g., HR=0.423 for DFS).
• Uses propensity score matching to generate 64 balanced patient pairs for analysis.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count for the final matched dataset is not explicitly stated.
• Data is from a single retrospective study, which may limit generalizability.

Provenance

Source

figshare, author Xiao Wu.

Collection Method

Retrospective research on patients treated with neoadjuvant immunochemotherapy.

Freshness

Last updated 2026-05-21 05:44:23; freshness should be verified.