BMI1 Expression and Pregnancy Outcomes in Endometrial Receptivity Study

BMI1 gene expression data from 117 endometrial tissue samples, including 78 elective abortion and 39 spontaneous abortion cases, links protein levels to clinical pregnancy results. Researcher Meili Liu published this clinical study dataset in April 2026. The 10.2 KB Excel file contains measurements from immunohistochemistry, qPCR, and western blot analyses.

Use Cases

• Correlate BMI1 protein expression levels from immunohistochemistry with clinical pregnancy and live birth outcomes.
• Analyze the diagnostic utility of BMI1 mRNA levels from qPCR for distinguishing spontaneous from elective abortion patient groups.
• Model the relationship between BMI1 status (positive/negative) and rates of biochemical pregnancy using ROC analysis results.
• Investigate co-expression patterns of BMI1 with upstream regulators like PR and E6AP or downstream effectors like GATA6 and NANOG.

Strengths

• 117 patient tissue samples provide a clinical foundation for analysis.
• Data integrates three measurement methods: IHC, qPCR, and western blot.
• Includes a two-year clinical follow-up cohort of 50 infertile patients for outcome validation.

Limitations

• Small sample size of 117 total tissue samples limits statistical power for subgroup analyses.
• Dataset scope is tiny at 10.2 KB, indicating limited raw data or aggregated results only.
• Geographic and demographic origins of patient samples are unspecified, potentially limiting generalizability.

Provenance

Source

figshare, authored by Meili Liu.

Collection Method

Endometrial tissues obtained from patient cohorts; BMI1 levels measured via IHC, qPCR, and WB.

Time Range

Study period unspecified; clinical follow-up covered two years.

Freshness

Last updated April 2026.

Geography

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