A 2026 dataset from figshare contains transcriptional data from purple sea urchin immune cells exposed to UVB radiation. Authored by Riss M. Kell, it likely includes gene expression profiles from single-cell RNA sequencing performed six hours post-exposure. The dataset investigates the crosstalk between DNA damage response and innate immune pathways.
Use Cases
- Analyze transcriptional activation of DDR genes based on UVB-induced genotoxic stress.
- Identify cell-type-specific responses based on single-cell RNA sequencing of phagocytes and vibratile cells.
- Study post-translational modification pathways based on ubiquitination and phosphorylation substrates.
- Compare DDR-immune crosstalk mechanisms based on data from a basal deuterostome model.
Strengths
- Data is derived from a long-lived, cancer-resistant model organism (Strongylocentrotus purpuratus).
- Includes results from functional assays and western blots confirming pathway activation.
- Licensed under CC-BY-4.0 for open reuse.
Limitations
- Row count is unknown, which may limit suitability assessment.
- Column-level documentation is absent; field semantics must be inferred after download.
- The dataset is very small (9.6 KB), indicating limited scope.
Provenance
- Source
- figshare
- Collection Method
- Single-cell RNA sequencing and functional assays on sea urchin coelomocytes.
- Freshness
- Last updated 2026-03-19 05:18:33.