Mouse Gut Microbiota Composition After Acute High-Intensity Exercise

A 15.2 KB dataset from figshare contains results from a study investigating dynamic alterations in gut microbiota following a 30-minute high-intensity treadmill run in BALB/c and C57BL/6 mice. Colonic content samples were collected at 0, 30, and 60 minutes post-exercise for 16S rRNA gene sequencing. The dataset, authored by Ruolin Gao and last updated in April 2026, shows strain-specific microbial changes and energy metabolism responses.

Use Cases

• Analyzing strain-specific differences in gut microbial diversity based on alpha and beta diversity metrics mentioned in the description.
• Investigating temporal dynamics of the Bacteroidetes/Firmicutes ratio based on post-exercise sampling time points.
• Studying the role of the genus Muribaculum as an exercise-responsive taxon potentially associated with gut motility.
• Comparing functional metabolic responses, such as energy recovery and anti-inflammatory capacity, between mouse strains.

Strengths

• Data is derived from a controlled experimental design with specific time points (0, 30, 60 minutes post-exercise).
• Findings include statistically significant results (p-values < 0.01, < 0.05, < 0.001) for microbial changes.
• The dataset is openly available under a CC-BY-4.0 license.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small (15.2 KB), indicating limited scope, likely containing summary results rather than raw sequencing data.

Provenance

Source

figshare, author Ruolin Gao.

Collection Method

Colonic content samples from mice were collected for 16S rRNA gene sequencing.

Time Range

Samples were collected immediately, 30 minutes, and 60 minutes post-exercise.

Freshness

Last updated 2026-04-22 16:31:41; freshness should be verified.

Geography

Laboratory study using mouse models; specific geographic location is unknown.