Table 3_ANCA-associated vasculitis is associated with an increased risk of cardiac and vas

A retrospective cohort study analyzing electronic health records from the US-based TriNetX network. The study includes 20,422 patients with granulomatosis with polyangiitis (GPA) and 5,907 with microscopic polyangiitis (MPA), matched 1:1 with control patients. It was authored by Sebastian Klapa and last updated in April 2026.

Use Cases

• Calculate hazard ratios for mortality and cardiovascular events based on the reported study results.
• Compare cardiovascular risk profiles between GPA and MPA patient cohorts.
• Analyze the association between ANCA-associated vasculitis and specific events like MACE or thromboembolism.
• Validate propensity score matching methodologies for retrospective cohort studies in electronic health records.

Strengths

• Includes a large patient cohort with 20,422 GPA and 5,907 MPA cases.
• Uses a 1:1 propensity-matched control cohort to optimize comparability.
• Reports specific hazard ratios for mortality, MACE, and thromboembolic events.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Data may reflect geographic bias inherent to the US-based TriNetX network.

Provenance

Source

Electronic health records database of the US-based TriNetX network.

Collection Method

Retrospective cohort study using propensity score matching.

Time Range

null

Freshness

Last updated 2026-04-15 05:45:58; freshness should be verified.

Geography

United States (based on the TriNetX network source).