UK Biobank Physical Activity and Inflammatory Bowel Disease Risk Study

Yitian Wei published a prospective cohort study on figshare analyzing data from 293,578 UK Biobank participants. The research evaluates the longitudinal relationship between self-reported physical activity intensity and the incidence of Crohn's disease and ulcerative colitis. The dataset was last updated on May 14, 2026.

Use Cases

• Assessing the protective effect of total physical activity on Crohn's disease risk based on multivariable Cox regression results.
• Investigating intensity-dependent relationships between moderate-to-vigorous activity and ulcerative colitis risk.
• Visualizing disease progression over time using cumulative event curves mentioned in the methods.
• Examining non-linear associations between activity levels and IBD incidence via restricted cubic spline analysis.

Strengths

• Large-scale cohort of 293,578 participants from the UK Biobank.
• Prospective study design with follow-up period and linked hospital admission and death registry records for case identification.
• Analysis includes multivariable Cox proportional hazards regression and non-linear modeling techniques.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Data may reflect geographic and demographic bias inherent to the UK Biobank source.

Provenance

Source

UK Biobank

Collection Method

Prospective cohort study analyzing self-reported physical activity data categorized by intensity.

Freshness

Last updated 2026-05-14 05:23:51; freshness should be verified.

Geography

United Kingdom