aMAP Score and Mortality in MASLD/MetALD/ALD Patients: NHANES 1999-2018 Cohort

A 1999-2018 cohort study of 32,654 participants from the U.S. National Health and Nutrition Examination Survey (NHANES) assesses the association between the aMAP risk score and mortality in patients with steatotic liver disease. The dataset includes results from multivariable Cox models, Kaplan-Meier curves, and an external validation cohort of 642 Southern Chinese patients. It was authored by Peng-yang Li and last updated in April 2026.

Use Cases

• Validate the aMAP risk score's predictive power for all-cause mortality based on the described cohort analysis.
• Investigate non-linear relationships between risk scores and mortality using the described restricted cubic spline methods.
• Compare mortality risk associations across MASLD, MetALD, and ALD subclassifications as outlined in the results.
• Assess the generalizability of findings using the described external validation cohort from Southern China.

Strengths

• Includes a large primary cohort of 32,654 participants from a nationally representative survey (NHANES).
• Provides external validation using an independent hospital-based cohort of 642 patients.
• Analyzes multiple mortality outcomes: all-cause, cardiovascular, and cancer.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is very small (20.0 KB), suggesting it contains summary results or a single table rather than raw patient-level data.

Provenance

Source

National Health and Nutrition Examination Survey (NHANES) and an independent hospital-based Southern Chinese cohort.

Collection Method

Cohort study using multivariable Cox proportional hazards models, restricted cubic spline analysis, and Kaplan-Meier curves.

Time Range

Primary data from NHANES cycles 1999 to 2018, with mortality follow-up through December 31, —2019.

Freshness

Last updated 2026-04-24 13:49:20; freshness should be verified.

Geography

United States (NHANES) and Southern China (validation cohort).