BKI-1748 Efficacy Data for Ovine Congenital Toxoplasmosis Treatment

91% lamb viability was achieved in sheep treated with the compound BKI-1748, compared to 52% in untreated controls. This 18.2 KB Excel file contains results from a study where 23 pregnant sheep were infected with Toxoplasma gondii and treated after IgM seroconversion. The dataset, authored by Roberto Sánchez-Sánchez and last updated in 2026, is shared under a CC-BY-4.0 license.

Use Cases

• Compare lamb viability rates based on treatment status mentioned in the results.
• Analyze IgG antibody level trends over time post-infection as described in the study.
• Model the correlation between congenital infection status and lamb birth weight from the reported findings.
• Evaluate prenatal treatment efficacy initiated after seroconversion, a key clinical scenario outlined in the background.

Strengths

• Specific efficacy metrics are provided, such as 91% vs. 52% lamb viability and 17% vs. 100% congenital infection rates.
• The experimental design is clearly described, including a treatment group of 10 sheep and a control group of 10.
• Data is shared under a permissive CC-BY-4.0 license for reuse.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is very small at 18.2 KB, indicating limited scope.

Provenance

Source

figshare

Collection Method

Experimental study involving oral inoculation of pregnant sheep and subsequent drug treatment.

Freshness

Last updated 2026-04-27 05:18:20; freshness should be verified.