Streptomyces sp. NELs-40: Genomic and Antibacterial Characterization Against MRSA

Mamy Jayne Nelly Rajaofera's research data, last updated in May 2026, characterizes the Streptomyces sp. strain NELs-40. The dataset includes genomic analysis results, such as a 7,973,786 bp genome with 49 biosynthetic gene clusters, and experimental data on the strain's antibacterial efficacy against Methicillin-resistant Staphylococcus aureus (MRSA).

Use Cases

• Comparative genomic analysis based on the reported 16S rRNA, ANI, AAI, and dDDH values for taxonomic classification.
• Identifying potential antimicrobial biosynthetic pathways based on the 30 predicted antimicrobial-related biosynthetic gene clusters (BGCs).
• Evaluating antibacterial compound efficacy based on reported MIC (125 μg/mL), inhibition zone (37 mm), and biofilm inhibition (32.25%) data against MRSA.
• Analyzing bioactive metabolite composition based on the 23 compounds identified via GC–MS, such as 9-octadecenoic acid methyl ester.

Strengths

• Genomic characterization is detailed, including a complete genome size of 7,973,786 bp and identification of 49 biosynthetic gene clusters.
• Experimental results are quantified, with specific metrics like a 37 mm inhibition zone and a Minimum Inhibitory Concentration (MIC) of 125 μg/mL against MRSA.
• The dataset is openly licensed under CC-BY-4.0, facilitating reuse.

Limitations

• The dataset is a 22.6 KB DOCX file, suggesting it is a summary table or document rather than a raw, machine-readable data repository.
• Column-level documentation is absent; field semantics must be inferred from the textual description after download.
• Row count is unknown, which may limit suitability assessment for computational analysis.

Provenance

Source

Mamy Jayne Nelly Rajaofera via figshare

Collection Method

Data generated from genomic sequencing (Illumina HiSeq X10), bioinformatic analysis (antiSMASH, CompareM, TYGS), and laboratory assays (well diffusion, MIC, GC–MS).

Freshness

Last updated 2026-05-29 06:07:47; freshness should be verified.