Table 3_Clinical characteristics and individualized treatment strategies for children with type 1 diabetes and exogenous insulin antibody syndrome: a retrospective case series and literature review.xlsx

Five pediatric patients with type 1 diabetes and exogenous insulin antibody syndrome were studied retrospectively from 2016 to 2026. Liang Zhang authored this case series, which includes data on demographics, laboratory findings, treatment regimens, and continuous glucose monitoring outcomes. The dataset is derived from a single center and was last updated in March 2026.

Use Cases

• Analyze the relationship between insulin antibody titers and glycemic control metrics like Time in Range (TIR) and Time Below Range (TBR).
• Compare the effectiveness of different insulin regimens (e.g., pump vs. multiple daily injections) on C-peptide levels and glucose variability (CV).
• Investigate the clinical response to immunosuppressive therapy (mycophenolate mofetil dosage) by tracking longitudinal autoantibody profiles and cytokine levels.
• Correlate patient demographics and clinical manifestations with specific treatment strategies and outcomes over four assessment time points.

Strengths

• Longitudinal data collected at four specific time points for immune and thyroid function parameters.
• Includes detailed continuous glucose monitoring (CGM) metrics (TIR, TBR, CV) for assessing glycemic control.

Limitations

• Extremely small sample size of only 5 patients limits statistical power and generalizability.
• Single-center, retrospective study design without a control group, as noted by the authors.
• Dataset size is 11.2 KB, indicating a very limited scope focused on a specific case series.

Provenance

Source

Retrospective case series from a single clinical center, authored by Liang Zhang.

Collection Method

Clinical data collection from pediatric patients diagnosed with T1DM and EIAS, supplemented by a literature review.

Time Range

Patient data from January 2016 to January 2026.

Freshness

Data covers patients up to January 2026, with the record last updated in March 2026.