Clinical Practice Guidelines for Early Psychosis Intervention: AGREE II Appraisal

Pasquale Scognamiglio's systematic review and appraisal of 26 international clinical practice guidelines and quality standards for early intervention in psychosis. The work, last updated in June 2026, identifies 32 core recommendations for treating clinical high-risk and first-episode psychosis populations. It includes a formal AGREE II quality assessment of the included documents.

Use Cases

• Benchmarking local service models against international guideline recommendations for clinical high-risk psychosis.
• Informing the design of specialized multidisciplinary teams based on consistently endorsed components for first-episode psychosis.
• Assessing the methodological quality of existing clinical guidelines using the AGREE II framework described in the review.

Strengths

• Includes 26 source documents (24 clinical practice guidelines and 2 quality standards) published from 2005 onward.
• Applies a formal, structured appraisal methodology (AGREE II) with inter-rater agreement assessed.
• Identifies 32 specific, guideline-derived core recommendations for service delivery.

Limitations

• The dataset is a single 11.7 KB DOCX file, indicating a very limited textual summary rather than the underlying review data.
• Row count and column-level documentation for any extracted data are unknown.
• The scope is restricted to documents published in English or Italian, which may introduce geographic or linguistic bias.

Provenance

Source

figshare, author Pasquale Scognamiglio.

Collection Method

Systematic review of MEDLINE, Cochrane Library, Web of Science, guideline repositories, and grey literature up to March 2025.

Time Range

Guidelines published from 2005 onward, with literature search up to March 2025.

Freshness

Last updated 2026-06-03 06:02:23.

Geography

International guidelines, but limited to those published in English or Italian.