Myxobacterial PilY1 Protein Diversity Across 67 Genomes

Sixty-seven representative myxobacterial genomes reveal PilY1 proteins are widely distributed, with an average of two homologs per genome. The dataset, created by Utkarsha Mahanta and last updated in May 2026, contains phylogenetic and structural analysis of these proteins, which are critical for bacterial motility and adhesion. It suggests an evolutionary strategy for tailoring bacterial surface machinery to diverse environmental demands.

Use Cases

• Phylogenetic classification of PilY1 proteins based on domain architecture and cysteine content described in the study
• Investigating functional specialization of bacterial adhesins based on N-terminal domain variation mentioned in the description
• Identifying potential horizontal gene transfer events based on the clustering of PilY1.3 with homologs from diverse phyla
• Studying conserved operon structures involving pilY1 genes and minor pilins (pilX, pilW, pilV, fimU) for pilus assembly

Strengths

• Analysis is based on 67 representative myxobacterial genomes, providing a defined taxonomic scope.
• Includes phylogenetic reconstruction identifying several well-supported clades based on taxonomy and protein features.
• Structural modeling predicts conserved interaction patterns, adding a functional dimension to the genomic data.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is small (86.1 KB), indicating limited scope, likely containing summary or analysis results rather than raw sequence data.

Provenance

Source

figshare, author Utkarsha Mahanta

Collection Method

Genomic, phylogenetic, and structural analysis of publicly available genome sequences.

Freshness

Last updated 2026-05-07 05:41:15; freshness should be verified.