Meta-Analysis of Astragalus mongholicus Bunge for Wound Healing in Animal Models

A systematic review and meta-analysis of 21 preclinical animal studies with 559 animals, evaluating the efficacy and safety of the traditional Chinese botanical drug Astragalus mongholicus Bunge for wound healing. The analysis was conducted by Jun Zhang, registered in PROSPERO (CRD420250641262), and last updated in April 2026. The data is compiled from a search of seven databases for randomized controlled studies comparing the treatment to placebo or no treatment.

Use Cases

• Assessing the pooled effect size of Astragalus mongholicus Bunge on wound contraction percentage based on the reported standardized mean difference.
• Evaluating the treatment's impact on biological markers like angiogenesis and collagen deposition based on the meta-analysis results.
• Comparing outcomes across different preclinical animal wound models based on the aggregated study data.
• Identifying gaps for future research based on the included 20 citations and study protocols.

Strengths

• Includes data from 21 studies involving 559 animals, providing a quantitative basis for analysis.
• Results are derived from a systematic review following a registered protocol (PROSPERO CRD420250641262).
• The meta-analysis reports specific effect metrics, such as a standardized mean difference of 4.18 for wound contraction.

Limitations

• Row count and column-level documentation are absent; field semantics must be inferred after download.
• The dataset is very small (16.7 KB), indicating limited raw data scope, likely containing summary statistics.
• Data may reflect publication or selection bias inherent to the systematic review's inclusion criteria.

Provenance

Source

Jun Zhang via figshare

Collection Method

Systematic search of seven databases for randomized controlled animal studies, with data extraction and analysis using R software.

Freshness

Last updated 2026-04-17 05:08:55