Table 3_Dose-dependent protective effects of Tripterygium wilfordii glycosides on joint an

A 2026 dataset from figshare by Shangwen Qi presents experimental results from a collagen-induced arthritis rat model. The data likely contains measurements of joint and lung pathology, cytokine expression, and gut microbiota composition from rats treated with different doses of Tripterygium wilfordii glycosides. The dataset is 24.6 KB in size and shared under a CC-BY-4.0 license.

Use Cases

• Analyzing dose-response relationships for drug efficacy based on treatment group data.
• Modeling associations between gut microbiota composition and inflammatory markers based on 16S rRNA sequencing and cytokine data.
• Investigating correlations between histological scores for joint/lung injury and molecular biomarker expression.
• Predicting microbial functional pathways related to short-chain fatty acid production based on PICRUSt2 predictions.

Strengths

• Includes data from multiple experimental groups (normal control, model, three dose groups, prednisolone control).
• Integrates multiple data types: histological scores, cytokine mRNA levels, protein expression, and 16S rRNA sequencing results.
• Clear experimental timeline with treatments from day 15 to 42 and sacrifice on day 43.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small (24.6 KB), indicating limited scope or summary-level data.

Provenance

Source

figshare, author Shangwen Qi

Collection Method

Experimental data from a controlled animal study using collagen-induced arthritis in Wistar rats.

Time Range

Experimental period from day 15 to day 43 post-induction.

Freshness

Last updated 2026-04-23 05:27:25