Network Meta-Analysis of Non-Pharmacological Diabetic Foot Ulcer Interventions

A 2026 network meta-analysis by Jiaxing Zheng synthesizes evidence from 24 randomized controlled trials. The study evaluates 15 different non-pharmacological interventions for diabetic foot ulcer healing, comparing outcomes like 12-week healing rate and healing time.

Use Cases

• Compare the effectiveness of 15 intervention types, such as Negative Pressure Wound Therapy + Standard Care, on the 12-week healing rate outcome.
• Analyze the relative performance of interventions like Gas Therapy + Dressing Therapy + Standard Care for the healing time metric.
• Examine the SUCRA rankings from the network meta-analysis to identify the most promising intervention strategies for clinical decision support.

Strengths

• Systematic review methodology searched 8 major databases including PubMed and Cochrane.
• Analysis includes 24 randomized controlled trials, providing a structured evidence base.
• Evaluates 15 distinct non-pharmacological intervention types for comparative effectiveness.

Limitations

• Evidence is derived from a limited number of small-sample primary studies, as noted in the conclusion.
• The certainty of evidence is limited, with wide confidence intervals reported for the findings.
• Dataset scope is limited to a 114.1 KB DOCX file containing the analysis report, not raw trial data.

Provenance

Source

figshare

Collection Method

Systematic review and network meta-analysis of published randomized controlled trials.

Time Range

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Freshness

Last updated March 2026.

Geography

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