Overview of Systematic Reviews on CPAP for Blood Pressure in Sleep Apnea

17 systematic reviews and meta-analyses were included in this umbrella review. The overview assesses the effect of continuous positive airway pressure (CPAP) on blood pressure in patients with obstructive sleep apnea (OSA). It evaluates methodological quality, evidence certainty, and citation overlap across the included reviews.

Use Cases

• Analyze the distribution of GRADE evidence certainty ratings (high, moderate, low, very low) across 109 evaluated outcomes from the included reviews.
• Assess the relationship between AMSTAR-2 methodological quality ratings and reported blood pressure outcomes across the 17 included systematic reviews.
• Examine the citation overlap matrix and corrected coverage area (14.2%) to understand redundancy among primary studies in the review literature.

Strengths

• Includes 17 systematic reviews and meta-analyses on a specific clinical question.
• Applies multiple standardized assessment tools (ROBIS, AMSTAR-2, PRISMA 2020, GRADE) for quality evaluation.
• Provides a quantitative citation overlap analysis with a calculated corrected coverage area of 14.2%.

Limitations

• The dataset is a single 266.7 KB DOCX file, limiting machine-readability and direct computational analysis.
• Methodological quality is low: 14 out of 17 (82.3%) included reviews were rated as low quality by AMSTAR-2.
• Evidence certainty is predominantly low: 76 out of 109 evaluated outcomes were rated as low or very low quality by GRADE.

Provenance

Source

Author: Jingjing Liu. Platform: figshare.

Collection Method

Umbrella review compiling systematic reviews and meta-analyses identified via search of PubMed, Embase, Cochrane Library, Web of Science, CNKI, VIP, Wanfang, and CBM databases.

Time Range

Literature search from database inception to December 1, 2025.

Freshness

Last updated March 24, 2026, with literature search up to December 1, 2025.

Geography

Reviews include studies from global sources and Chinese databases (CNKI, VIP, Wanfang, CBM).