Common Carp Cathepsin L Gene Expression Profiles Across Tissues

Nine cathepsin L paralogs in common carp show tissue-specific expression patterns, including enrichment at mucosal barriers and in systemic immune hubs. Sagar Nayak published this analysis of gene expression data in 2026. The dataset is a 17.7 KB document detailing expression divergence across tissues and immune compartments.

Use Cases

• Analyze tissue-specific expression patterns of ctsl.1A/B and ctslaA/B paralogs across mucosal barriers and systemic immune hubs.
• Model structural variation in protease loop architecture and active-site cleft geometry to predict divergent substrate preferences.
• Correlate ctsl expression dynamics with inflammatory cytokine induction during Sphaerospora molnari infection.
• Investigate expression reprogramming of proteolytic profiles in circulating blood and head kidney leukocytes over disease progression.

Strengths

• Identifies nine distinct cathepsin L paralogs retained after duplication events.
• Documents expression partitioning across specific tissues and immune compartments.
• Includes structural modeling predictions for protease variants.
• Released under a permissive CC-BY-4.0 license.

Limitations

• Dataset is very small at 17.7 KB, indicating limited raw data or a summary document.
• Unknown row count and column structure for quantitative analysis.
• Focus is restricted to a single species, the common carp.

Provenance

Source

figshare, authored by Sagar Nayak.

Collection Method

Gene identification, expression analysis, and structural modeling from the common carp model.

Time Range

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Freshness

Last updated in April 2026.

Geography

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