Table 3_Exploring the celecoxib–cervical cancer relationship using in vitro, network pharm

A 756.4 KB Excel file contains results from a study investigating the anticancer role of celecoxib. The research combined in vitro assays, network pharmacology, and Mendelian randomization analyses to identify mechanisms. The dataset was authored by Tongfei Wang and last updated on May 19, 2026.

Use Cases

• Validate drug-target hypotheses based on NEU1 inhibition data
• Analyze causal relationships in cervical cancer risk using Mendelian randomization results
• Study immune pathway mediation based on T-cell and CD25-related findings
• Correlate in vitro assay results (proliferation, migration) with genetic proxy data

Strengths

• Integrates three distinct methodological approaches: in vitro assays, network pharmacology, and Mendelian randomization
• Provides specific causal inference metrics (OR = 0.736, 95% CI: 0.566–0.958) and mediation percentage (28.458%)
• Released under a CC-BY-4.0 license, allowing for open reuse

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• Data may reflect methodological bias inherent to the specific experimental and analytical approaches used

Provenance

Source

figshare

Collection Method

Results from a research study combining laboratory experiments and statistical genetics analyses.

Freshness

Last updated 2026-05-19 05:41:46; freshness should be verified