TMS Motor Resonance Data on Cortical Excitability and Inhibition

Figshare hosts a neurophysiology dataset from a study using single-pulse Transcranial Magnetic Stimulation (spTMS) to measure motor evoked potentials (MEPs). The research investigated links between GABAergic and glutamatergic mechanisms of cortical excitability and muscle-specific motor resonance during action observation. Data includes pre- and post-action observation measurements from protocols like intracortical facilitation (ICF) and short-interval intracortical inhibition (SICI) for the FDI and ADM hand muscles.

Use Cases

• Analyze correlations between pre-AO SICI measures in the ADM muscle and SP-induced MEP suppression during index finger movement observation.
• Model the relationship between post-AO ICF values in the ADM muscle and the strength of ADM responses during little finger movement observation.
• Compare corticospinal excitability, measured via SP-induced MEPs in the FDI and ADM muscles, across different observed action conditions (e.g., index vs. little finger movements).
• Examine changes in MEP amplitudes from ICF, SP, and SICI protocols before and after the action observation task to assess task-induced neurophysiological modulation.

Strengths

• Data originates from a controlled neurophysiological experiment using established Transcranial Magnetic Stimulation (TMS) protocols.
• Includes specific excitability indices (SP, ICF, SICI) that probe distinct glutamatergic and GABAergic mechanisms.
• Dataset is openly shared under a CC BY 4.0 license, facilitating reuse and analysis.

Limitations

• The dataset is small in scale, with a file size of 130.2 KB, indicating limited sample size or number of observations.
• Specific structural details like row count, column names, and sample data are unavailable, complicating preliminary assessment.
• Data collection methodology and participant demographics are not detailed in the provided description, limiting understanding of sample representativeness.

Provenance

Source

Aynur Ragimova via figshare

Collection Method

Data collected using single-pulse Transcranial Magnetic Stimulation (spTMS) during an action observation task involving video stimuli of finger movements.

Time Range

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Freshness

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Geography

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