Table 3_Genomic analysis reveals multi-level resistance network linking oxidative stress p

A study of 282 Klebsiella pneumoniae strains from the United Arab Emirates tested for antibiotic susceptibility, with 96 strains undergoing whole-genome sequencing. The data was authored by Lana Daoud and last updated on May 15, 2026. It explores mutations in oxidative stress pathways and their association with resistance to the antibiotic cefiderocol.

Use Cases

• Identify genetic markers for cefiderocol resistance based on mutations in iron uptake and oxidative stress genes.
• Analyze clonal evolution of high-risk Klebsiella pneumoniae clones based on genomic sequence data.
• Investigate multi-pathway resistance networks based on co-mutation patterns across functional gene categories.
• Correlate phenotypic susceptibility profiles with genotypic data for antibiotic resistance surveillance.

Strengths

• Includes whole-genome sequencing data for 96 representative bacterial strains.
• Correlates phenotypic susceptibility results for 282 strains with genotypic analyses.
• Focuses on a specific, high-priority pathogen (Klebsiella pneumoniae) and a novel antibiotic (cefiderocol).

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Data may reflect geographic bias inherent to the collection from the United Arab Emirates.

Provenance

Source

figshare

Collection Method

Whole-genome sequencing and bioinformatic analysis of bacterial isolates.

Freshness

Last updated 2026-05-15 05:27:50; freshness should be verified.

Geography

United Arab Emirates