Lactococcus cremoris FBMS_5810: Genomic and Preclinical Probiotic Evaluation

A genomic and preclinical evaluation of the probiotic candidate Lactococcus cremoris FBMS_5810, authored by Ioanna Farmakioti and published on figshare in April 2026. The dataset likely contains results from genomic analyses and in vivo mouse studies assessing strain-specific genes, microbiota modulation, and intestinal gene expression changes. The file is 19.4 KB in size and is licensed under CC-BY-4.0.

Use Cases

• Identify probiotic candidate genes based on genomic characterization of adhesion, colonization, and pathogen exclusion.
• Analyze gut microbiota modulation based on changes in the relative abundance of families like Muribaculaceae and Ruminococcaceae.
• Evaluate intestinal immune response based on changes in gene expression of Tnf, Il1b, and Zo1.
• Assess probiotic safety and efficacy for translational applications based on integrated genomic and preclinical data.

Strengths

• Dataset integrates genomic characterization with in vivo preclinical evaluation, providing a systematic approach.
• The file is openly licensed under CC-BY-4.0, facilitating reuse.
• The description details specific microbial families and genes affected, providing concrete biological insights.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is very small (19.4 KB), indicating limited scope or a summary table.

Provenance

Source

figshare

Collection Method

Genomic analysis and preclinical in vivo studies in mice, as described.

Freshness

Last updated 2026-04-29 05:37:53; freshness should be verified.