Clinical Trial Data for High-Dose aiTBS Treatment of Gait and Cognitive Functions in CSVD

36 patients with cerebral small vessel disease (CSVD) participated in a randomized, single-blind, sham-controlled trial conducted by Xiao-Ying Zhao. The dataset includes primary and secondary outcome measures for gait and cognitive function, assessed at baseline, post-intervention, and a 4-week follow-up. Results were last updated on June 1, 2026.

Use Cases

• Analyzing the efficacy of accelerated intermittent theta burst stimulation (aiTBS) based on changes in 3-meter Timed Up and Go (3mTUG) duration.
• Investigating correlations between treatment response and neuroimaging features based on periventricular white matter hyperintensity and total CSVD burden scores.
• Comparing multidimensional functional outcomes between real and sham stimulation groups based on Tinetti, CMMS, and MoCA assessment scores.
• Modeling longitudinal treatment effects on gait parameters based on three-dimensional gait analysis data collected at multiple time points.

Strengths

• Data originates from a controlled clinical trial with 36 patients (19 real, 17 sham), providing a structured experimental basis.
• Includes multidimensional assessments covering gait, cognitive, affective, and autonomic nervous function.
• Measures were taken at three time points (baseline, post-intervention, 4-week follow-up), allowing for longitudinal analysis.

Limitations

• The dataset is very small at 17.7 KB, indicating limited scope and sample size.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for certain analyses.

Provenance

Source

Xiao-Ying Zhao via figshare

Collection Method

Data collected from a randomized, single-blind, sham-controlled clinical trial.

Freshness

Last updated 2026-06-01 05:24:47; freshness should be verified.