HMMR Gene Expression and Prognostic Data for Oral Squamous Cell Carcinoma

A 30.5 KB dataset from a multi-cohort bioinformatics analysis, last updated on 2026-06-04. It contains results from a study by Lingling Liu integrating transcriptomic data from the TCGA OSCC cohort and two GEO cohorts (GSE37991, GSE41613). The data likely includes differential expression, survival analysis, and immune correlation results for the HMMR gene and other prognostic markers in oral cancer.

Use Cases

• Validate HMMR as a prognostic biomarker based on its reported association with survival outcomes.
• Analyze correlations between gene expression and immune cell infiltration, such as Th2 cells, as described in the study.
• Investigate gene networks and pathways, like cell cycle regulation and DNA repair, linked to HMMR in oral squamous cell carcinoma.
• Perform secondary analysis on the identified common differentially expressed genes (DEGs) across the integrated cohorts.

Strengths

• Data is derived from integrated analysis of three established public cohorts (TCGA, GSE37991, GSE41613).
• The study reports specific statistical results, such as HMMR's predictive AUC of 0.919 and correlation coefficients with immune cells.
• Released under a permissive CC-BY-4.0 license for reuse.

Limitations

• Row count and column-level documentation are unknown, requiring manual inspection after download.
• The dataset's 30.5 KB size suggests it contains summary or analysis results, not raw transcriptomic data.
• Freshness should be verified as the last update is dated in the future (2026-06-04).

Provenance

Source

Integrated analysis of transcriptomic data from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) cohorts GSE37991 and GSE41613.

Collection Method

Bioinformatics analysis including differential expression, survival analysis, immune infiltration, and pathway enrichment.

Freshness

Last updated 2026-06-04 22:02:16; freshness should be verified.