Hnrnpa1 Knockout Zebrafish Phenotype and Metabolic Profiling Data

A dataset from a novel zebrafish knockout model investigating the RNA binding proteins Hnrnpa1 and Hnrnpa3. The data likely contains phenotypic and metabolic profiling results, including lipid metabolism changes, from double mutant embryos. The dataset was authored by Lara U. Jansen and last updated on June 1, 2026.

Use Cases

• Analyze developmental defects in zebrafish embryos based on the described muscle and vascular phenotypes
• Investigate changes in lipid metabolism based on the severe metabolic profile alterations mentioned
• Study genetic compensation or redundancy between duplicated genes based on the single versus double mutant phenotypes
• Identify potential therapeutic targets for HNRNPA-associated diseases based on the implicated cellular pathways

Strengths

• Dataset is focused on a novel genetic model system for studying Hnrnpa1 function
• Includes metabolic profiling data revealing lipid metabolism changes
• Published under a permissive CC-BY-4.0 license for reuse

Limitations

• Row count is unknown, which may limit suitability assessment
• Column-level documentation is absent; field semantics must be inferred after download
• The dataset is small (14.0 KB), indicating limited scope

Provenance

Source

figshare

Collection Method

Likely generated from laboratory experiments involving zebrafish knockout models and metabolic profiling.

Freshness

Last updated 2026-06-01 05:36:17; freshness should be verified