Table 3_Hybrid plasmids: genetic diversity and hypervirulent phenotype of Klebsiella pneum

A 2026 study by Svetlana Kovalchuk analyzes hybrid plasmids in Klebsiella pneumoniae. The dataset includes whole-genome sequencing results from 32 isolates collected from patients and surfaces in eight Russian hospitals, with virulence assessed via mouse lethality assays. It also incorporates a cluster analysis of 295 hybrid plasmids from a global population.

Use Cases

• Analyzing the co-occurrence of virulence and resistance genes based on the description of hybrid plasmids.
• Clustering plasmid sequences based on replicon type, ARGs, and virulence genes as described in the results.
• Investigating the association between specific sequence types (ST147, ST395, ST11) and hybrid plasmid carriage.
• Assessing bacterial virulence phenotypes in relation to genetic markers like iucABCD, iutA, and rmpA2.

Strengths

• Includes whole-genome sequencing data from 32 distinct bacterial isolates.
• Incorporates a global comparative analysis of 295 hybrid plasmid sequences.
• Pairs genomic data with experimental virulence assessment (mouse lethality assay for 7 isolates).
• Released under a permissive CC-BY-4.0 license.

Limitations

• Dataset scale is limited at 36.1 KB; the primary data may be summarized results rather than raw sequences.
• Column-level documentation is absent; field semantics must be inferred after download.
• Data may reflect geographic bias inherent to the sample collection from Russian hospitals.

Provenance

Source

Svetlana Kovalchuk, via figshare.

Collection Method

Whole-genome sequencing of clinical and environmental isolates, cluster analysis of plasmid sequences.

Time Range

Study published in 2026; specific collection period not stated.

Freshness

Last updated 2026-04-29 06:02:24.

Geography

Isolates recovered from eight hospitals in Russia.