Table 3_Identification of shared biomarkers in obesity and non-alcoholic fatty liver disea

Two shared biomarkers (NCAPH and IRS2) identified through Mendelian randomization and transcriptomic analysis of obesity and non-alcoholic fatty liver disease (NAFLD). The dataset was created by Jian Wang and uploaded to figshare on April 29, 2026. Mendelian randomization indicated a significant causal effect of obesity on NAFLD.

Use Cases

• Predicting obesity risk based on biomarker expression levels mentioned in the description
• Predicting NAFLD risk based on biomarker expression levels mentioned in the description
• Analyzing causal relationships between metabolic diseases using Mendelian randomization results
• Building regulatory networks linking lncRNAs (NEAT1, MALAT1, FTX) and miRNAs to shared biomarkers

Strengths

• Identifies two specific biomarkers (NCAPH and IRS2) with validated expression changes
• Results are based on a combination of Mendelian randomization and transcriptomic data analysis
• Includes validation via qRT-PCR for NCAPH

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• The dataset is 9.6 KB, indicating a very limited scope of data

Provenance

Source

figshare

Collection Method

Analysis of GWAS and GEO database summary statistics and transcriptome data

Freshness

Last updated 2026-04-29 05:58:20; freshness should be verified