Table 3_Integrated transcriptome-microbiome analysis reveals a host-microbe interplay asso

2,566 commonly upregulated and 994 commonly downregulated genes were identified across resistant Aedes albopictus populations from five sites in Guangdong and Hainan provinces, China. The dataset integrates transcriptome sequencing, 16S rRNA gut microbiome analysis, and kdr mutation detection to explore host-microbe interactions linked to beta-cypermethrin resistance. It was authored by Lifang Liu and last updated on 2026-04-22.

Use Cases

• Identify candidate genes associated with insecticide resistance based on transcriptome analysis.
• Analyze correlations between gut microbiome composition (e.g., Cedecea abundance) and resistance phenotypes.
• Investigate the role of specific kdr mutations (F1534C, F1534L, F1534S, V1016G) in target-site resistance.
• Model host-microbe interactions that influence mosquito survival under insecticide exposure.

Strengths

• Integrates multiple data types: transcriptomics, microbiome sequencing, and kdr mutation detection.
• Includes experimental validation via dietary supplementation assays with Cedecea neteri.
• Covers five geographic sites in Guangdong and Hainan provinces, China.
• Provides specific resistance ratios (RR50 ranging from 2.84 to 29.18) and mutation frequencies (49.4% to 100.0%).

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Data may reflect geographic bias inherent to the collection sites in southern China.

Provenance

Source

figshare, authored by Lifang Liu.

Collection Method

Field collection, bioassays, transcriptome sequencing, 16S rRNA sequencing, and correlation analysis.

Time Range

Collection date is unspecified; dataset was updated in 2026.

Freshness

Last updated 2026-04-22 05:46:33; freshness should be verified.

Geography

Five sites in Guangdong and Hainan provinces, China.