Table 3_Microbiota-metabolites interaction associated with glycemic improvement following

Table 3_Microbiota-metabolites interaction associated with glycemic improvement following a dietary herbal intervention in type 2 diabetes.xlsx is a dataset from a translational study investigating gut microbiome and serum metabolite changes linked to blood glucose regulation. The study involved a clinical cohort of 385 patients with type 2 diabetes and complementary animal experiments, with data published by Bingbing Li on figshare under CC-BY-4.0 license. The dataset was last updated on 2026-04 13.

Use Cases

• Identify microbial taxa mediating glycemic improvement based on longitudinal clinical and animal study data.
• Analyze serum metabolite profiles, including branched-chain amino acid pathways, as potential intermediaries in metabolic regulation.
• Validate causal relationships between gut microbiota and glucose outcomes using fecal microbiota transplantation experiment results.
• Perform mediation analysis to delineate pathways linking specific bacteria like Alistipes shahii to metabolites like phenyllactic acid.

Strengths

• Data is derived from a substantial clinical cohort of 385 patients with type 2 diabetes.
• Includes longitudinal monitoring of glucose levels, gut microbiota, and serum metabolites across multiple time points.
• Integrates translational evidence from both human clinical trials and animal model experiments, including FMT.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

Bingbing Li via figshare.

Collection Method

Prospective clinical cohort study and complementary animal experiments, including fecal microbiota transplantation and serum metabolomic profiling.

Time Range

The longitudinal study monitored patients across multiple time points, but specific dates are not provided.

Freshness

Last updated 2026-04-13 05:39:32; freshness should be verified.

Geography

Geographic coverage of the clinical cohort is not specified.