Hypothalamic miRNA Expression in Sunite Sheep Under Three Photoperiods

Sunite sheep were studied to investigate the effects of photoperiod on hypothalamic microRNA regulation. The dataset contains results from miRNA-sequencing analysis of three photoperiod conditions with three biological replicates per group. Yajing Shao authored the dataset, which was last updated on 2026-04-21.

Use Cases

• Identify differentially expressed miRNAs based on photoperiod condition comparisons (SP vs. LP, SP vs. SLP, LP vs. SLP).
• Construct co-expression networks based on DEMs and their predicted target mRNAs.
• Perform functional annotation analysis based on KEGG pathways like GnRH, prolactin, VEGF, and Wnt signaling.
• Validate candidate miRNAs (e.g., oar-miR-370-5p, oar-miR-10b, oar-miR-3957-3p) for their role in seasonal estrus.

Strengths

• Includes three biological replicates per experimental group, which may improve statistical reliability.
• Identifies specific counts of differentially expressed miRNAs (57, 47, and 12) between photoperiod comparisons.
• Functional analysis links target genes to specific KEGG pathways relevant to reproduction.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small (8.9 KB), indicating limited scope, likely containing summary results rather than raw sequencing data.

Provenance

Source

figshare, author Yajing Shao.

Collection Method

miRNA-sequencing technology applied to Sunite sheep hypothalamic tissue.

Freshness

Last updated 2026-04-21 05:36:33; freshness should be verified.