Yak Cardiac Transcriptomic and Proteomic Data Under Nutritional Supplementation

Yiqun Chen published an integrative transcriptomic-proteomic atlas of yak cardiac tissue on figshare in April 2026. The dataset contains results from a 60-day intervention study comparing ad libitum grazing with winter supplementary feeding in 12 male Muli yaks. It includes differential expression analysis yielding 140 differentially expressed genes and 254 differentially expressed proteins.

Use Cases

• Identify biomarkers for nutritional status based on the coordinated induction of selenoproteins GPX1 and SELENOW.
• Study post-transcriptional regulation based on the decoupling between transcriptional and translational landscapes described.
• Analyze immune response attenuation based on the downregulation of stress-responsive effectors like ULBP13 and GZMB.
• Investigate redox fortification pathways in cardiac tissue based on the activation of the selenoproteome.

Strengths

• Integrates two molecular data layers: RNA sequencing and data-independent acquisition mass spectrometry.
• Includes specific differential expression results: 140 DEGs and 254 DEPs.
• Provides concrete fold-change values for key markers, such as GPX1 and SELENOW.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is small (22.4 KB), indicating limited scope or summary-level data.

Provenance

Source

figshare, author Yiqun Chen.

Collection Method

Data from a completely randomized 60-day intervention study with myocardial specimens interrogated via RNA sequencing and mass spectrometry.

Time Range

Study period was 60 days.

Freshness

Last updated 2026-04-14 12:38:57; freshness should be verified.

Geography

Qinghai-Tibet Plateau.