Quinolone-Associated Pemphigoid Reports from FDA FAERS Database

183 reports of pemphigoid linked to quinolone antibiotics, analyzed from the FDA Adverse Event Reporting System (FAERS). The dataset includes disproportionality analysis results and subgroup analyses by age, sex, and reporter type. It was authored by Xin Li and last updated on 2026-04 15.

Use Cases

• Identify disproportionality signals for specific quinolone antibiotics based on reporting odds ratios (RORs).
• Analyze demographic patterns in adverse event reporting based on subgroup analyses by age and sex.
• Investigate latency patterns for drug-induced pemphigoid based on the reported onset within 30 days.
• Correlate findings from spontaneous reporting systems with published literature evidence.

Strengths

• Contains 183 specific case reports of quinolone-associated pemphigoid.
• Provides disproportionality metrics (ROR, PRR, BCPNN) for specific drugs like ofloxacin (ROR=2.75).
• Includes subgroup analyses by age, sex, and reporter type, as mentioned in the description.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small (9.7 KB), indicating limited scope.

Provenance

Source

FDA Adverse Event Reporting System (FAERS) database.

Collection Method

Analysis of spontaneous adverse event reports using disproportionality methods.

Time Range

The temporal coverage of the underlying FAERS data is not specified.

Freshness

Last updated 2026-04-15 05:22:42; freshness should be verified.

Geography

Likely global, as FAERS collects international reports, but the specific geography is not stated.