Mouse Gut Microbiota and Metabolite Data from a 17-Week Obesity Study

Table 3_Portulaca oleracea polysaccharide alleviates obesity in mice with long-term high-fat diet by regulating gut microbiota and metabolites.xlsx contains experimental data from a 17-week mouse study investigating the anti-obesity effects of a polysaccharide. The dataset, authored by Qiang Fu and last updated in March 2026, includes analyzed parameters on obesity, gut microbiota diversity, and serum metabolites. It is hosted on figshare under a CC-BY-4.0 license.

Use Cases

• Correlating changes in specific gut microbiota genera (e.g., Firmicutes/Bacteroidetes ratio) with obesity indices.
• Analyzing the relationship between altered serum metabolites (e.g., LacCer, NDC) and improved glucose homeostasis.
• Modeling the impact of a polysaccharide dietary supplement on lipid profile parameters in a high-fat diet model.
• Investigating host-microbiome metabolic interactions through integrated microbiota and metabolomics data.

Strengths

• Data is derived from a controlled 17-week animal experiment with a defined intervention (3.2% POP).
• Analysis includes multiple data modalities: obesity parameters, gut microbiota profiling, and serum metabolomics.
• Dataset is openly available under a permissive CC-BY-4.0 license for reuse.

Limitations

• Row count and specific column definitions are unknown, requiring manual inspection after download.
• The dataset is very small (38.4 KB), indicating it likely contains summary or processed results rather than raw sequencing/spectra data.
• Description metadata is limited; actual data quality and completeness require verification.

Provenance

Source

Qiang Fu via figshare.

Collection Method

Data generated from a laboratory experiment where C57BL/6J mice were fed a high-fat diet supplemented with Portulaca oleracea polysaccharide for 17 weeks.

Time Range

The experimental period covered 17 weeks; specific calendar dates are not provided.

Freshness

Last updated 2026-03-18 07:38:46.