Nosema ceranae Gene Expression Under Phytogenic Treatment in Honey Bees

Transcriptome profiling data from a controlled laboratory experiment where honey bees infected with the parasite Nosema ceranae were treated with Bidens pilosa extract. The dataset, authored by Yi-Hsuan Li and last updated in June 2026, includes samples collected at 5, 10, and 20 days post-infection. It is a small dataset of 125.2 KB, shared under a CC-BY-4.0 license.

Use Cases

• Analyzing stage-dependent gene expression changes in Nosema ceranae based on the described transcriptomic profiles at 5, 10, and 20 days post-infection.
• Investigating the impact of phytogenic treatments on parasite metabolic pathways based on the described suppression of V-type ATPase and ion transport processes.
• Correlating transcriptomic changes with host survival and pathogen load based on the described experimental results linking treatment to improved survival probability.
• Validating potential drug targets in microsporidian parasites based on the described RNAi-mediated knockdown of V-type ATPase components.

Strengths

• Data is derived from controlled laboratory cage experiments with defined treatment groups of 50 bees per replicate.
• Transcriptomic analysis covers multiple time points (5, 10, and 20 days post-infection) allowing for temporal dynamics study.
• The dataset is openly shared under a permissive CC-BY-4.0 license.

Limitations

• Row count and column-level documentation are unknown, which may limit suitability assessment.
• The dataset's scale is limited at 125.2 KB, suggesting a focused experimental scope rather than a broad survey.
• Description metadata is limited; actual data structure and quality require manual inspection after download.

Provenance

Source

Yi-Hsuan Li, shared via figshare.

Collection Method

Generated from transcriptome profiling of N. ceranae from infected honey bee midguts in controlled laboratory experiments.

Time Range

Samples collected at 5, 10, and 20 days post-infection.

Freshness

Last updated 2026-06-03 09:29:10; freshness should be verified.