Table 3_Reinfection and ceftriaxone tolerance in a clinical case of recurrent gonorrhoea:

Four clinical isolates of Neisseria gonorrhoeae obtained between 2022 and 2025 were analyzed for ceftriaxone tolerance using disc testing, growth curves, MDK99 assays, and a Galleria mellonella infection model. Whole-genome sequencing compared strain types across episodes. The dataset, authored by Izumo Kanesaka and last updated in April 2026, supports a case report on recurrent gonorrhoea.

Use Cases

• Analyzing bacterial killing kinetics based on MDK99 values across different ceftriaxone concentrations.
• Comparing genomic sequence types to distinguish between reinfection and within-host persistence.
• Modeling infection outcomes based on data from the Galleria mellonella in vivo model.
• Correlating tolerance disc test results with growth curve data for clinical isolates.

Strengths

• Includes data from four distinct clinical isolates collected over a multi-year period (2022-2025).
• Integrates multiple complementary assays: tolerance disc testing, growth curves, MDK99, and an in vivo model.
• Dataset is openly available under a CC-BY-4.0 license.

Limitations

• Row count and column-level documentation are unknown, which may limit suitability assessment.
• The dataset is very small (17.3 KB), indicating a limited scope focused on a specific case series.
• Description metadata is limited; actual data structure and field semantics must be inferred after download.

Provenance

Source

figshare

Collection Method

Clinical isolates underwent laboratory assays including tolerance disc testing, growth curves, MDK99 measurement, and a Galleria mellonella infection model; whole-genome sequencing was performed.

Time Range

2022 to 2025

Freshness

Last updated 2026-04-23 05:35:00