Carbapenem-Resistant Enterobacteriaceae in Pediatric Patients from Eastern China

Yihan Zheng's dataset contains 281 non-duplicated clinical isolates of Carbapenem-resistant Enterobacteriaceae (CRE) from children in Suzhou, eastern China. The data includes antimicrobial susceptibility profiles, prevalence of carbapenemase and ESBL genes, and hypervirulence-associated gene detection in Klebsiella pneumoniae strains. The dataset was last updated on 2026-05-28.

Use Cases

• Analyze the distribution of carbapenemase genes (e.g., blaOXA-232, blaKPC-2) among CRE isolates based on the prevalence statistics provided.
• Investigate the co-occurrence of antimicrobial resistance and hypervirulence in Klebsiella pneumoniae strains based on the reported detection of iucA and rmpA genes.
• Study the clinical prognosis of patients infected with carbapenem-resistant and hypervirulent Klebsiella pneumoniae (CR-HVKP) based on the description of patient outcomes.

Strengths

• Contains data on 281 non-duplicated clinical isolates, providing a specific sample size.
• Reports precise prevalence percentages for specific resistance genes (e.g., blaOXA-232 at 38.08%) and bacterial species (e.g., Klebsiella pneumoniae at 55.87%).
• Links clinical strain data to patient prognosis information for a subset of cases.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for specific analytical tasks.
• Data may reflect geographic and temporal bias inherent to a single study location and period.

Provenance

Source

Yihan Zheng via figshare.

Collection Method

Clinical strains were isolated, identified via mass spectrometry, and analyzed for antimicrobial susceptibility and associated genes via PCR and sequencing.

Freshness

Last updated 2026-05-28 05:58:22; freshness should be verified.

Geography

Suzhou, eastern China.