Case Report of a 47-Year Tonsillar Cancer Trajectory with Genomic Data

A single, detailed clinical case report documents a patient with tonsillar adenoid cystic carcinoma over a 47-year disease trajectory from 1977 to 2024. The report includes a timeline of treatments, recurrences, and molecular profiling results from a 2018 recurrence. The document was authored by Mingzhu Wang and shared under a CC-BY-4.0 license in June 2026.

Use Cases

• Study the clinical progression of a rare cancer based on the detailed 47-year timeline of diagnosis, recurrence, and metastasis.
• Analyze treatment responses and outcomes based on the documented surgical, radiotherapeutic, and chemotherapeutic interventions.
• Investigate genomic correlates of late-stage progression based on the reported NOTCH2, MTOR, and SPEN variants from the 2018 recurrence.

Strengths

• Documents an extremely rare 47-year clinical course, one of the longest reported for this cancer.
• Integrates detailed clinical history with specific molecular profiling data from a late recurrence.
• Shared under a permissive CC-BY-4.0 license for reuse.

Limitations

• Contains only a single case report, limiting statistical analysis and generalizability.
• The data is unstructured text within a 14.9 KB DOCX file, requiring manual extraction for computational use.
• Column-level documentation is absent; field semantics must be inferred after download.

Provenance

Source

figshare

Collection Method

Clinical case documentation and genomic analysis.

Time Range

Patient history from 1977 to 2024.

Freshness

Last updated 2026-06-02 04:28:44; freshness should be verified.